Drug Discovery Companies  
     
 
    Challenges
 
     
  Small to Medium sized Drug Discovery companies face several challenges when it comes to Target Discovery and Validation

The key challenges that this segment faces are:

  • Lack of adequate Clinical Data for Statistical Significance
  • The need to perform in silico prototyping and screening to accelerate discovery and minimize expenses
  • Non-availability of full range of genomic platforms for Expression Studies during Target Discovery:  eg. Microarray, qPCR, Gene Expression Profiling and Genotyping platforms
  • Non-availability of full range of genomic platforms for Expression Studies during Target Validation:  RNAi, Cell Lines, Cell Based Studies etc.
 
 
    Solutions
 
     
 
Integrated Target Discovery and Validation Solutions

Polyclone provides target discovery and validation services in contract-based and turnkey models. We offer a combination of clinical samples and data (through our partners), wide range of platform technologies (wet lab and in silico), and an expert scientific team to address the challenges faced by Drug Discovery Companies.

Target Discovery Workflow

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  • In silico Target Discovery and Validation Services

Polyclone offers the following in silico approaches to augment customer’s lab based drug discovery research:

 
 
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Bioinformatics Services for Comparative Analysis:

Polylcone offers the following in silico Genomic analysis services :
            • Comparative genomics
            • Phylogeny studies
            • Gene expression analysis
            • Protein function  Predictions,
            • Interaction networks
            • Modeling,
            • Structure actively relationship studies
            • Drug designing using docking methods and QSAR
 
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  Integrated Target Discovery and Validation Solutions  
  In silico Target Discovery and Validation Services  
  Bioinformatics Services for Comparative Analysis  
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