Case Study  
     
     Automation of capture sequence and probe design  
     
 

Customer:

  • US based nano-biotech company

Key Customer Challenges:

  • Customer is a developer of assay technology for colorimetric detection of amplified DNA sequences using nano-particle probe technology. The nanoparticle probes change color based on the presence of a specific DNA target and function as permanent test record when spotted onto a membrane.
  • Customer required a custom tool to design capture sequences for unique regions and probe sequences for common regions between the input sequences for use with their technology.
 
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  Solution Overview
  • Custom Bioinformatics Application developed for requirement
  • The application was developed to accept an input of at least two or more sequences (CDS) of a single gene or gene sequences from different organisms or species
  • Application generated capture sequences in a complementary fashion to certain unique regions on each of the input sequence like SNPs
  • Application generated probe sequences that were down stream to the capture sequences
  • For each input sequence, the capture sequences and the probes would be generated and displayed along with their properties
 
   
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  Key Benefits to Customer
  • Automated a highly manual process
  • Stringent design to ensure quality and consistency
  • Inclusion of software along with platform facilitated for customizability of experimental input & design
 
     
     
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