BioSuppliers  
     
 
    Challenges
 
     
  From Reagents to Oligos, from Chemicals to Chips, bio-suppliers provide the critical ingredients for Biotech research. Bio-Suppliers are under constant pressure from their customers to offer better quality materials, at competitive pricing and to provide for a more flexible ordering system. The challenges faced by this segment include:
  • The need to continuously introduce new products that meet the ever increasing high quality and low price demands of customers while having to beat well entrenched & “industry standard” competition.
  • To offer flexible and customized order fulfillment to customers who have varied needs driven by usage of disparate high throughput and combichem technologies. 
  • To ensure that customers make use of their products to the optimal extent, by packaging experiment design and data analysis tools
  
     
 
    Solutions
 
     
  Polyclone provides a range of lab based and computational services that address the challenges faced by Bio Suppliers:

Contract Research

Polyclone offers exploratory research and investigative services on a contractual model. These contract services enable customers to decrease time and costs to market by leveraging Polyclone’s expertise in research and development, bioprocess scale-up, pilot scale manufacturing, technology and economic assessments. Areas of expertise include:

  • Chemical Reagents
  • Recombinant DNA Services
  • Specialty Oligonucleotides design and analysis
  • Cell based Transfection/assays
  • Assay development for screening
  • Qualitative/quantitative assays for detection
  • Viral load testing
  
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Product Validation & Comparative Studies

Whether it is a new transfection reagent that needs to be compared with the industry standard or a novel oligo-array that has be taken to market, Polyclone provides independent validation services that help customers get an unbiased perspective about their products, enabling them to make the right strategic and market moves. 

Polyclone provides benchmarking studies (with industry standards or competitive products) using sophisticated molecular biology lab facilities and follows that up with the requisite data analysis to provide a holistic solution to the customers.

Polyclone has access to a wide range of technologies in-house and through partnerships, and can perform comparative studies across a range of industry leading platforms in

  • Microarrays
  • qPCR
  • Genotyping and
  • Gene Expression Profiling
 
Click here to learn how we helped a reputed Bio-Supplier decrease their time to market for a Transfection Reagent
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Bioinformatics Tools and Services

  • Nucleic Acid Design and Analysis:

    Polyclone offers comprehensive Nucleic acid design and analysis 6services for Microarray and PCR requirements for various applications including SNPs, Gene Expression Studies, CGH, Chip-on-Chip and Pathogen Detection. Using a combination of industry recommended as well as proprietary algorithms and neural network techniques, Polyclone provides stringent oligo design followed with in-depth Microarray/ qPCR data analysis services. Algorithms have been developed for the design and analysis of:
    • Probes
    • Primers
    • Taqman
    • Molecular Beacons
    • Scorpions
    • Lightcycler
    • siRNA
    • miRNA
    • LNA

These can either be offered as a service or a web-based/ off-line tool can be developed.
 
Click here to learn how we designed a long-oligo based array for a bacterial genome for a German Microarray Technology company
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  • Custom Application Development and Maintenance:

    Polyclone’s software consulting team offers custom application development and maintenance services for various requirements. Some examples:

    • Experiment Design and Reporting: Bioinformatics Applications that help end-customers in optimally using the R&D supplies, effective design of the experiment and thorough analysis of the output data.
    • Automated Ordering: Integration of instrumentation with order-placement system to automate ordering from the suppliers, in a ‘just in time’ and flexible manner.
Click here to learn how we integrated an automated oligo ordering system in a PCR based assay validation process
   
    • Custom Genomic and Proteomic Alogrithms : -   Design of Custom Algorithms for specific genomic and proteomic problems
Click here to learn how our consultants developed an application for capture sequences and probes for the input genomic or CDS sequences
   
    • Experiment Design and Reporting: Bioinformatics Applications that are embedded with the Platform to help end-customers in using them optimally, designing the experiment and analyzing the resultant data
Click here to learn how we developed an application for qPCR primer design for a Germany High Throughput equipment developer
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  Contract Research  
  Product Validation & Comparative Studies  
  Bioinformatics Tools and Services  
   
Nucleic Acid Design and Analysis
Custom Application Development and Maintenance
 
       
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